Endothelin potentiates TRPV1 via ET(A )receptor-mediated activation of protein kinase C

BACKGROUND: Endothelin-1 (ET-1) both stimulates nociceptors and sensitizes them to noxious stimuli, an effect probably mediated by the ET(A )receptor (ET(A)R) expressed in sensory neurons. The cellular mechanisms of this ET-1-mediated effect are only poorly understood. TRPV1, the heat-, pH- and caps...

Descripción completa

Detalles Bibliográficos
Autores principales: Plant, Tim D, Zöllner, Christian, Kepura, Frauke, Mousa, Shaaban S, Eichhorst, Jenny, Schaefer, Michael, Furkert, Jens, Stein, Christoph, Oksche, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206006/
https://www.ncbi.nlm.nih.gov/pubmed/18001466
http://dx.doi.org/10.1186/1744-8069-3-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206006/
https://www.ncbi.nlm.nih.gov/pubmed/18001466
http://dx.doi.org/10.1186/1744-8069-3-35

Ejemplares similares