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Characterization, developmental expression and evolutionary features of the huntingtin gene in the amphioxus Branchiostoma floridae
BACKGROUND: Huntington's disease is an inherited neurodegenerative disorder that is caused by the expansion of an N-terminal polyQ stretch in the huntingtin protein. In order to investigate the hypothesis that huntingtin was already involved in development of the nervous system in the last comm...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206037/ https://www.ncbi.nlm.nih.gov/pubmed/18005438 http://dx.doi.org/10.1186/1471-213X-7-127 |