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Constitutive upregulation of the transforming growth factor-β pathway in rheumatoid arthritis synovial fibroblasts

Genome-wide gene expression was comparatively investigated in early-passage rheumatoid arthritis (RA) and osteoarthritis (OA) synovial fibroblasts (SFBs; n = 6 each) using oligonucleotide microarrays; mRNA/protein data were validated by quantitative PCR (qPCR) and western blotting and immunohistoche...

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Detalles Bibliográficos
Autores principales: Pohlers, Dirk, Beyer, Andreas, Koczan, Dirk, Wilhelm, Thomas, Thiesen, Hans-Jürgen, Kinne, Raimund W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206335/
https://www.ncbi.nlm.nih.gov/pubmed/17594488
http://dx.doi.org/10.1186/ar2217