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Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
Current evidence implicates intervertebral disc degeneration as a major cause of low back pain, although its pathogenesis is poorly understood. Numerous characteristic features of disc degeneration mimic those seen during ageing but appear to occur at an accelerated rate. We hypothesised that this i...
Autores principales: | Le Maitre, Christine Lyn, Freemont, Anthony John, Hoyland, Judith Alison |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206356/ https://www.ncbi.nlm.nih.gov/pubmed/17498290 http://dx.doi.org/10.1186/ar2198 |
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