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Selenium supplementation in critically ill patients: can too much of a good thing be a bad thing?

A recent study by Forceville and colleagues evaluated the effect of high-dose selenium administration as a treatment for septic shock. The study was negative and conflicts with existing clinical data regarding selenium administration in critically ill patients. Perhaps the key to understanding the d...

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Detalles Bibliográficos
Autor principal: Heyland, Daren K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206521/
https://www.ncbi.nlm.nih.gov/pubmed/17692136
http://dx.doi.org/10.1186/cc5975
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author Heyland, Daren K
author_facet Heyland, Daren K
author_sort Heyland, Daren K
collection PubMed
description A recent study by Forceville and colleagues evaluated the effect of high-dose selenium administration as a treatment for septic shock. The study was negative and conflicts with existing clinical data regarding selenium administration in critically ill patients. Perhaps the key to understanding the differences between these discrepant observations lies in considering the dose and timing of selenium administration.
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spelling pubmed-22065212008-01-19 Selenium supplementation in critically ill patients: can too much of a good thing be a bad thing? Heyland, Daren K Crit Care Commentary A recent study by Forceville and colleagues evaluated the effect of high-dose selenium administration as a treatment for septic shock. The study was negative and conflicts with existing clinical data regarding selenium administration in critically ill patients. Perhaps the key to understanding the differences between these discrepant observations lies in considering the dose and timing of selenium administration. BioMed Central 2007 2007-08-07 /pmc/articles/PMC2206521/ /pubmed/17692136 http://dx.doi.org/10.1186/cc5975 Text en Copyright © 2007 BioMed Central Ltd
spellingShingle Commentary
Heyland, Daren K
Selenium supplementation in critically ill patients: can too much of a good thing be a bad thing?
title Selenium supplementation in critically ill patients: can too much of a good thing be a bad thing?
title_full Selenium supplementation in critically ill patients: can too much of a good thing be a bad thing?
title_fullStr Selenium supplementation in critically ill patients: can too much of a good thing be a bad thing?
title_full_unstemmed Selenium supplementation in critically ill patients: can too much of a good thing be a bad thing?
title_short Selenium supplementation in critically ill patients: can too much of a good thing be a bad thing?
title_sort selenium supplementation in critically ill patients: can too much of a good thing be a bad thing?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206521/
https://www.ncbi.nlm.nih.gov/pubmed/17692136
http://dx.doi.org/10.1186/cc5975
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