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GnRH and LHR gene variants predict adverse outcome in premenopausal breast cancer patients

BACKGROUND: Breast cancer development and progression are dependent on estrogen activity. In premenopausal women, estrogen production is mainly regulated through the hypothalamic-pituitary-gonadal (HPG) axis. METHODS: We have investigated the prognostic significance of two variants of genes involved...

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Detalles Bibliográficos
Autores principales:	Piersma, Djura, Themmen, Axel PN, Look, Maxime P, Klijn, Jan GM, Foekens, John A, Uitterlinden, André G, Pols, Huibert AP, Berns, Els MJJ
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206727/ https://www.ncbi.nlm.nih.gov/pubmed/17692113 http://dx.doi.org/10.1186/bcr1756

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