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Dermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factors
BACKGROUND: It has been well established that human fetuses will heal cutaneous wounds with perfect regeneration. Insulin-like growth factors are pro-fibrotic fibroblast mitogens that have important roles in both adult wound healing and during development, although their relative contribution toward...
Autores principales: | Rolfe, Kerstin J, Cambrey, Alison D, Richardson, Janette, Irvine, Laurie M, Grobbelaar, Adriaan O, Linge, Claire |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211318/ https://www.ncbi.nlm.nih.gov/pubmed/17988375 http://dx.doi.org/10.1186/1471-213X-7-124 |
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