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Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5)

BACKGROUND: Multidrug resistance is a particular limitation to cancer chemotherapy, antibiotic treatment and HIV medication. The ABC (ATP binding cassette) transporters human P-glycoprotein (ABCB1) and the human MRP5 (ABCC5) are involved in multidrug resistance. RESULTS: In order to elucidate struct...

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Detalles Bibliográficos
Autores principales:	Ravna, Aina W, Sylte, Ingebrigt, Sager, Georg
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211457/ https://www.ncbi.nlm.nih.gov/pubmed/17803828 http://dx.doi.org/10.1186/1742-4682-4-33

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