Expression of a Cu,Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of neuroblastoma cells to infectious injury

BACKGROUND: Infections can aggravate the course of neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). Mutations in the anti-oxidant enzyme Cu,Zn superoxide dismutase (EC 1.15.1.1, SOD1) are associated with familial ALS. Streptococcus pneumoniae, the most frequent respiratory p...

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Detalles Bibliográficos
Autores principales: Goos, Miriam, Zech, Wolf-Dieter, Jaiswal, Manoj Kumar, Balakrishnan, Saju, Ebert, Sandra, Mitchell, Timothy, Carrì, Maria Teresa, Keller, Bernhard U, Nau, Roland
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211486/
https://www.ncbi.nlm.nih.gov/pubmed/17997855
http://dx.doi.org/10.1186/1471-2334-7-131

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