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Intermediates in the Assembly and Degradation of Class I Major Histocompatibility Complex (MHC) Molecules Probed with Free Heavy Chain–specific Monoclonal Antibodies
Unassembled (free) heavy chains appear during two stages of the class I MHC molecule's existence: immediately after translation but before assembly with peptide and β(2)-microglobulin, and later, upon disintegration of the heterotrimeric complex. To characterize the structures of folding and de...
Autores principales: | Machold, Robert P., Ploegh, Hidde L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211561/ https://www.ncbi.nlm.nih.gov/pubmed/8976180 |
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