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The Activation Status of Neuroantigen-specific T Cells in the Target Organ Determines the Clinical Outcome of Autoimmune Encephalomyelitis

The clinical picture of experimental autoimmune encephalomyelitis (EAE) is critically dependent on the nature of the target autoantigen and the genetic background of the experimental animals. Potentially lethal EAE is mediated by myelin basic protein (MBP)–specific T cells in Lewis rats, whereas tra...

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Detalles Bibliográficos
Autores principales:	Kawakami, Naoto, Lassmann, Silke, Li, Zhaoxia, Odoardi, Francesca, Ritter, Thomas, Ziemssen, Tjalf, Klinkert, Wolfgang E.F., Ellwart, Joachim W., Bradl, Monika, Krivacic, Kimberly, Lassmann, Hans, Ransohoff, Richard M., Volk, Hans-Dieter, Wekerle, Hartmut, Linington, Christopher, Flügel, Alexander
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211765/ https://www.ncbi.nlm.nih.gov/pubmed/14734524 http://dx.doi.org/10.1084/jem.20031064

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