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CD4(+)CD25(+) T Regulatory Cells Dependent on ICOS Promote Regulation of Effector Cells in the Prediabetic Lesion

CD4(+)CD25(+) T regulatory cells (Tregs) prevent autoimmune disease, yet little is known about precisely where they exert their influence naturally in a spontaneous autoimmune disorder. Here, we report that Tregs and T effector cells (Teffs) coexist within the pancreatic lesion before type 1 diabete...

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Detalles Bibliográficos
Autores principales:	Herman, Ann E., Freeman, Gordon J., Mathis, Diane, Benoist, Christophe
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211778/ https://www.ncbi.nlm.nih.gov/pubmed/15184501 http://dx.doi.org/10.1084/jem.20040179

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