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Low Dose Leishmania major Promotes a Transient T Helper Cell Type 2 Response That Is Down-regulated by Interferon γ–producing CD8(+) T Cells

An unresolved issue in the field of T helper (Th) cell development relates to the findings that low doses of antigen promote Th2 cell development in vitro, whereas several classic in vivo studies suggest the opposite. Here we resolve this paradox by studying the early immune response in mice after i...

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Detalles Bibliográficos
Autores principales: Uzonna, Jude E., Joyce, Karen L., Scott, Phillip
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211781/
https://www.ncbi.nlm.nih.gov/pubmed/15184505
http://dx.doi.org/10.1084/jem.20040172