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CD25(+) CD4(+) T Cells, Expanded with Dendritic Cells Presenting a Single Autoantigenic Peptide, Suppress Autoimmune Diabetes

In the nonobese diabetic (NOD) mouse model of type 1 diabetes, the immune system recognizes many autoantigens expressed in pancreatic islet β cells. To silence autoimmunity, we used dendritic cells (DCs) from NOD mice to expand CD25(+) CD4(+) suppressor T cells from BDC2.5 mice, which are specific f...

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Detalles Bibliográficos
Autores principales:	Tarbell, Kristin V., Yamazaki, Sayuri, Olson, Kara, Toy, Priscilla, Steinman, Ralph M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211787/ https://www.ncbi.nlm.nih.gov/pubmed/15184500 http://dx.doi.org/10.1084/jem.20040180

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