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Surface μ Heavy Chain Signals Down-Regulation of the V(D)J-Recombinase Machinery in the Absence of Surrogate Light Chain Components

Early B cell development is characterized by stepwise, ordered rearrangement of the immunoglobulin (Ig) heavy (HC) and light (LC) chain genes. Only one of the two alleles of these genes is used to produce a receptor, a phenomenon referred to as allelic exclusion. It has been suggested that pre–B cel...

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Detalles Bibliográficos
Autores principales:	Galler, Gunther R., Mundt, Cornelia, Parker, Mathew, Pelanda, Roberta, Mårtensson, Inga-Lill, Winkler, Thomas H.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211789/ https://www.ncbi.nlm.nih.gov/pubmed/15173209 http://dx.doi.org/10.1084/jem.20031523

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