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Human Mannose-binding Lectin in Immunity: Friend, Foe, or Both?
Human mannose-binding lectin (MBL) recognizes a wide range of microorganisms and triggers the most ancient pathway of complement activation. However, ∼5% of individuals lack functional serum MBL and have not been found to be prone to severe infections in prospective studies. These data suggest that...
Autores principales: | Casanova, Jean-Laurent, Abel, Laurent |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211810/ https://www.ncbi.nlm.nih.gov/pubmed/15148331 http://dx.doi.org/10.1084/jem.20040537 |
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