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Exogenous Pathogen and Plant 15-Lipoxygenase Initiate Endogenous Lipoxin A(4) Biosynthesis

Lipoxin A(4) (LXA(4)) is a potent endogenous lipoxygenase-derived eicosanoid with antiinflammatory and proresolving properties. Supraphysiological levels of LXA(4) are generated during infection by Toxoplasma gondii, which in turn reduces interleukin (IL) 12 production by dendritic cells, thus dampe...

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Detalles Bibliográficos
Autores principales: Bannenberg, Gerard L., Aliberti, Julio, Hong, Song, Sher, Alan, Serhan, Charles
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211821/
https://www.ncbi.nlm.nih.gov/pubmed/14970178
http://dx.doi.org/10.1084/jem.20031325

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