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Developmental Separation of V(D)J Recombinase Expression and Initiation of IgH Recombination in B Lineage Progenitors In Vivo
In B lineage progenitors, V(D)J recombination occurs only during distinct stages of development and is restricted to immunoglobulin loci. This process is thought to be controlled by both regulated expression of the V(D)J recombinase and by limited accessibility of target loci to the recombinase comp...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211822/ https://www.ncbi.nlm.nih.gov/pubmed/14769853 http://dx.doi.org/10.1084/jem.20031802 |