CTLA-4–Ig Activates Forkhead Transcription Factors and Protects Dendritic Cells from Oxidative Stress in Nonobese Diabetic Mice

Prediabetes and diabetes in nonobese diabetic (NOD) mice have been targeted by a variety of immunotherapies, including the use of a soluble form of cytotoxic T lymphocyte antigen 4 (CTLA-4) and interferon (IFN)-γ. The cytokine, however, fails to activate tolerogenic properties in dendritic cells (DC...

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Detalles Bibliográficos
Autores principales: Fallarino, Francesca, Bianchi, Roberta, Orabona, Ciriana, Vacca, Carmine, Belladonna, Maria L., Fioretti, Maria C., Serreze, David V., Grohmann, Ursula, Puccetti, Paolo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211844/
https://www.ncbi.nlm.nih.gov/pubmed/15492127
http://dx.doi.org/10.1084/jem.20040942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211844/
https://www.ncbi.nlm.nih.gov/pubmed/15492127
http://dx.doi.org/10.1084/jem.20040942

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