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The Role of CXCR4 in Maintaining Peripheral B Cell Compartments and Humoral Immunity

The chemokine receptor CXCR4 is expressed in B cells at multiple stages of their development. CXCR4 function in humoral immunity has not been fully investigated. We have generated gene-targeted mice in which CXCR4 can be selectively inactivated in B cells and have shown that it is required for reten...

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Detalles Bibliográficos
Autores principales: Nie, Yuchun, Waite, Janelle, Brewer, Faraha, Sunshine, Mary-Jean, Littman, Dan R., Zou, Yong-Rui
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211858/
https://www.ncbi.nlm.nih.gov/pubmed/15520246
http://dx.doi.org/10.1084/jem.20041185