Pregnancy-associated Malaria and the Prospects for Syndrome-specific Antimalaria Vaccines

Aided by the Plasmodium falciparum genome project, recent discoveries regarding the molecular basis of malaria pathogenesis have led to a better understanding of the interactions between host and parasite. Although vaccines that prevent infection by malaria parasites remain only hopes for the future...

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Detalles Bibliográficos
Autores principales: Smith, Joseph D., Deitsch, Kirk W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211864/
https://www.ncbi.nlm.nih.gov/pubmed/15520241
http://dx.doi.org/10.1084/jem.20041974
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author Smith, Joseph D.
Deitsch, Kirk W.
author_facet Smith, Joseph D.
Deitsch, Kirk W.
author_sort Smith, Joseph D.
collection PubMed
description Aided by the Plasmodium falciparum genome project, recent discoveries regarding the molecular basis of malaria pathogenesis have led to a better understanding of the interactions between host and parasite. Although vaccines that prevent infection by malaria parasites remain only hopes for the future, there are now more immediate prospects for vaccines that protect against specific disease syndromes. Here, we discuss the latest advances in the development of a vaccine that specifically targets pregnancy-associated malaria (PAM).
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spelling pubmed-22118642008-03-11 Pregnancy-associated Malaria and the Prospects for Syndrome-specific Antimalaria Vaccines Smith, Joseph D. Deitsch, Kirk W. J Exp Med Commentary Aided by the Plasmodium falciparum genome project, recent discoveries regarding the molecular basis of malaria pathogenesis have led to a better understanding of the interactions between host and parasite. Although vaccines that prevent infection by malaria parasites remain only hopes for the future, there are now more immediate prospects for vaccines that protect against specific disease syndromes. Here, we discuss the latest advances in the development of a vaccine that specifically targets pregnancy-associated malaria (PAM). The Rockefeller University Press 2004-11-01 /pmc/articles/PMC2211864/ /pubmed/15520241 http://dx.doi.org/10.1084/jem.20041974 Text en Copyright © 2004, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Smith, Joseph D.
Deitsch, Kirk W.
Pregnancy-associated Malaria and the Prospects for Syndrome-specific Antimalaria Vaccines
title Pregnancy-associated Malaria and the Prospects for Syndrome-specific Antimalaria Vaccines
title_full Pregnancy-associated Malaria and the Prospects for Syndrome-specific Antimalaria Vaccines
title_fullStr Pregnancy-associated Malaria and the Prospects for Syndrome-specific Antimalaria Vaccines
title_full_unstemmed Pregnancy-associated Malaria and the Prospects for Syndrome-specific Antimalaria Vaccines
title_short Pregnancy-associated Malaria and the Prospects for Syndrome-specific Antimalaria Vaccines
title_sort pregnancy-associated malaria and the prospects for syndrome-specific antimalaria vaccines
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211864/
https://www.ncbi.nlm.nih.gov/pubmed/15520241
http://dx.doi.org/10.1084/jem.20041974
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