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Potentiation of C1 Esterase Inhibitor by StcE, a Metalloprotease Secreted by Escherichia coli O157:H7

The complement system is an essential component of host defense against pathogens. Previous research in our laboratory identified StcE, a metalloprotease secreted by Escherichia coli O157:H7 that cleaves the serpin C1 esterase inhibitor (C1-INH), a major regulator of the classical complement cascade...

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Detalles Bibliográficos
Autores principales:	Lathem, Wyndham W., Bergsbaken, Tessa, Welch, Rodney A.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211892/ https://www.ncbi.nlm.nih.gov/pubmed/15096536 http://dx.doi.org/10.1084/jem.20030255

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