Transgenic Expression of Decoy Receptor 3 Protects Islets from Spontaneous and Chemical-induced Autoimmune Destruction in Nonobese Diabetic Mice

Decoy receptor 3 (DCR3) halts both Fas ligand– and LIGHT-induced cell deaths, which are required for pancreatic β cell damage in autoimmune diabetes. To directly investigate the therapeutic potential of DCR3 in preventing this disease, we generated transgenic nonobese diabetic mice, which overexpres...

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Detalles Bibliográficos
Autores principales: Sung, Hsiang-Hsuan, Juang, Jyuhn-Huarng, Lin, Yu-Chun, Kuo, Chien-Hung, Hung, Jung-Tung, Chen, An, Chang, Der-Ming, Chang, Sun-Yran, Hsieh, Shie-Liang, Sytwu, Huey-Kang
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211895/
https://www.ncbi.nlm.nih.gov/pubmed/15078896
http://dx.doi.org/10.1084/jem.20031939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211895/
https://www.ncbi.nlm.nih.gov/pubmed/15078896
http://dx.doi.org/10.1084/jem.20031939

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