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Defective Suppressor Function of Human CD4(+) CD25(+) Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II
In autoimmune polyglandular syndromes (APS), several organ-specific autoimmune diseases are clustered. Although APS type I is caused by loss of central tolerance, the etiology of APS type II (APS-II) is currently unknown. However, in several murine models, depletion of CD4(+) CD25(+) regulatory T ce...
Autores principales: | Kriegel, Martin A., Lohmann, Tobias, Gabler, Christoph, Blank, Norbert, Kalden, Joachim R., Lorenz, Hanns-Martin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211900/ https://www.ncbi.nlm.nih.gov/pubmed/15117972 http://dx.doi.org/10.1084/jem.20032158 |
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