CD43 Regulation of T Cell Activation Is Not through Steric Inhibition of T Cell–APC Interactions but through an Intracellular Mechanism

CD43 is a large heavily glycosylated protein highly expressed on T cells and actively excluded from the immunological synapse through interactions with ezrin-radixin-moesin proteins. Due to its size and charge, it has been proposed that the CD43 ectodomain acts as a physical barrier to T cell–APC in...

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Detalles Bibliográficos
Autores principales: Tong, Jiankun, Allenspach, Eric J., Takahashi, Stephenie M., Mody, Purvi D., Park, Chan, Burkhardt, Janis K., Sperling, Anne I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211903/
https://www.ncbi.nlm.nih.gov/pubmed/15117976
http://dx.doi.org/10.1084/jem.20021602

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