SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors

Two papers describing mice deficient in signaling lymphocyte activation molecule and 2B4 represent the first accounts of immune phenotypes in animals lacking members of the SLAM family of receptors. The findings provide definitive evidence of the importance of SLAM-related receptors in the regulatio...

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Detalles Bibliográficos
Autor principal: Veillette, André
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211906/
https://www.ncbi.nlm.nih.gov/pubmed/15123741
http://dx.doi.org/10.1084/jem.20040588
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author Veillette, André
author_facet Veillette, André
author_sort Veillette, André
collection PubMed
description Two papers describing mice deficient in signaling lymphocyte activation molecule and 2B4 represent the first accounts of immune phenotypes in animals lacking members of the SLAM family of receptors. The findings provide definitive evidence of the importance of SLAM-related receptors in the regulation of T cell, macrophage, and natural killer cell functions.
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spelling pubmed-22119062008-03-11 SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors Veillette, André J Exp Med Commentary Two papers describing mice deficient in signaling lymphocyte activation molecule and 2B4 represent the first accounts of immune phenotypes in animals lacking members of the SLAM family of receptors. The findings provide definitive evidence of the importance of SLAM-related receptors in the regulation of T cell, macrophage, and natural killer cell functions. The Rockefeller University Press 2004-05-03 /pmc/articles/PMC2211906/ /pubmed/15123741 http://dx.doi.org/10.1084/jem.20040588 Text en Copyright © 2004, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Veillette, André
SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors
title SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors
title_full SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors
title_fullStr SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors
title_full_unstemmed SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors
title_short SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors
title_sort slam family receptors regulate immunity with and without sap-related adaptors
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211906/
https://www.ncbi.nlm.nih.gov/pubmed/15123741
http://dx.doi.org/10.1084/jem.20040588
work_keys_str_mv AT veilletteandre slamfamilyreceptorsregulateimmunitywithandwithoutsaprelatedadaptors

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