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Plasmodium falciparum Associated with Severe Childhood Malaria Preferentially Expresses PfEMP1 Encoded by Group A var Genes

Parasite-encoded variant surface antigens (VSAs) like the var gene–encoded Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family are responsible for antigenic variation and infected red blood cell (RBC) cytoadhesion in P. falciparum malaria. Parasites causing severe malaria in nonimmu...

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Detalles Bibliográficos
Autores principales: Jensen, Anja T.R., Magistrado, Pamela, Sharp, Sarah, Joergensen, Louise, Lavstsen, Thomas, Chiucchiuini, Antonella, Salanti, Ali, Vestergaard, Lasse S., Lusingu, John P., Hermsen, Rob, Sauerwein, Robert, Christensen, Jesper, Nielsen, Morten A., Hviid, Lars, Sutherland, Colin, Staalsoe, Trine, Theander, Thor G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211911/
https://www.ncbi.nlm.nih.gov/pubmed/15123742
http://dx.doi.org/10.1084/jem.20040274