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NKG2D Recognition and Perforin Effector Function Mediate Effective Cytokine Immunotherapy of Cancer
Single and combination cytokines offer promise in some patients with advanced cancer. Many spontaneous and experimental cancers naturally express ligands for the lectin-like type-2 transmembrane stimulatory NKG2D immunoreceptor; however, the role this tumor recognition pathway plays in immunotherapy...
Autores principales: | Smyth, Mark J., Swann, Jeremy, Kelly, Janice M., Cretney, Erika, Yokoyama, Wayne M., Diefenbach, Andreas, Sayers, Thomas J., Hayakawa, Yoshihiro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211920/ https://www.ncbi.nlm.nih.gov/pubmed/15545356 http://dx.doi.org/10.1084/jem.20041522 |
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