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Statins Inhibit HIV-1 Infection by Down-regulating Rho Activity

Human immunodeficiency virus (HIV)-1 infectivity requires actin-dependent clustering of host lipid raft–associated receptors, a process that might be linked to Rho guanosine triphosphatase (GTPase) activation. Rho GTPase activity can be negatively regulated by statins, a family of drugs used to trea...

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Detalles Bibliográficos
Autores principales:	del Real, Gustavo, Jiménez-Baranda, Sonia, Mira, Emilia, Lacalle, Rosa Ana, Lucas, Pilar, Gómez-Moutón, Concepción, Alegret, Marta, Peña, Jose María, Rodríguez-Zapata, Manuel, Alvarez-Mon, Melchor, Martínez-A., Carlos, Mañes, Santos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211926/ https://www.ncbi.nlm.nih.gov/pubmed/15314078 http://dx.doi.org/10.1084/jem.20040061

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