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CCR7 Signals Are Essential for Cortex–Medulla Migration of Developing Thymocytes
Upon TCR-mediated positive selection, developing thymocytes relocate within the thymus from the cortex to the medulla for further differentiation and selection. However, it is unknown how this cortex–medulla migration of thymocytes is controlled and how it controls T cell development. Here we show t...
Autores principales: | Ueno, Tomoo, Saito, Fumi, Gray, Daniel H.D., Kuse, Sachiyo, Hieshima, Kunio, Nakano, Hideki, Kakiuchi, Terutaka, Lipp, Martin, Boyd, Richard L., Takahama, Yousuke |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211934/ https://www.ncbi.nlm.nih.gov/pubmed/15302902 http://dx.doi.org/10.1084/jem.20040643 |
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