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CCR7 Signals Are Essential for Cortex–Medulla Migration of Developing Thymocytes

Upon TCR-mediated positive selection, developing thymocytes relocate within the thymus from the cortex to the medulla for further differentiation and selection. However, it is unknown how this cortex–medulla migration of thymocytes is controlled and how it controls T cell development. Here we show t...

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Detalles Bibliográficos
Autores principales: Ueno, Tomoo, Saito, Fumi, Gray, Daniel H.D., Kuse, Sachiyo, Hieshima, Kunio, Nakano, Hideki, Kakiuchi, Terutaka, Lipp, Martin, Boyd, Richard L., Takahama, Yousuke
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211934/
https://www.ncbi.nlm.nih.gov/pubmed/15302902
http://dx.doi.org/10.1084/jem.20040643

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