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Multiple Distinct Sets of Stereotyped Antigen Receptors Indicate a Role for Antigen in Promoting Chronic Lymphocytic Leukemia

Previous studies suggest that the diversity of the expressed variable (V) region repertoire of the immunoglobulin (Ig)H chain of B-CLL cells is restricted. Although limited examples of marked constraint in the primary structure of the H and L chain V regions exist, the possibility that this level of...

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Detalles Bibliográficos
Autores principales: Messmer, Bradley T., Albesiano, Emilia, Efremov, Dimitar G., Ghiotto, Fabio, Allen, Steven L., Kolitz, Jonathan, Foa, Robin, Damle, Rajendra N., Fais, Franco, Messmer, Davorka, Rai, Kanti R., Ferrarini, Manlio, Chiorazzi, Nicholas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211936/
https://www.ncbi.nlm.nih.gov/pubmed/15314077
http://dx.doi.org/10.1084/jem.20040544