Cargando…
CD27 Expression Promotes Long-Term Survival of Functional Effector–Memory CD8(+)Cytotoxic T Lymphocytes in HIV-infected Patients
Human immunodeficiency virus (HIV)-specific CD8(+) T cells persist in high frequencies in HIV-infected patients despite impaired CD4(+) T helper response to the virus, but, unlike other differentiated effector cytotoxic T lymphocytes, most continue to express the tumor necrosis factor receptor famil...
Autores principales: | Ochsenbein, Adrian F., Riddell, Stanley R., Brown, Michele, Corey, Lawrence, Baerlocher, Gabriela M., Lansdorp, Peter M., Greenberg, Philip D. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211945/ https://www.ncbi.nlm.nih.gov/pubmed/15583014 http://dx.doi.org/10.1084/jem.20040717 |
Ejemplares similares
-
Restoration of CD28 Expression in CD28(−) CD8(+) Memory Effector T Cells Reconstitutes Antigen-induced IL-2 Production
por: Topp, Max S., et al.
Publicado: (2003) -
Siglec-7 represents a glyco-immune checkpoint for non-exhausted effector memory CD8+ T cells with high functional and metabolic capacities
por: Haas, Quentin, et al.
Publicado: (2022) -
Modulating CD27 signaling to treat cancer
por: Riether, Carsten, et al.
Publicado: (2012) -
CD8 exerts differential effects on the deployment of cytotoxic T lymphocyte effector functions
por: Laugel, Bruno, et al.
Publicado: (2007) -
Elimination of chronic viral infection by blocking CD27 signaling
por: Matter, Matthias, et al.
Publicado: (2006)