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T Cell Cross-Reactivity and Conformational Changes during TCR Engagement

All thymically selected T cells are inherently cross-reactive, yet many data indicate a fine specificity in antigen recognition, which enables virus escape from immune control by mutation in infections such as the human immunodeficiency virus (HIV). To address this paradox, we analyzed the fine spec...

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Detalles Bibliográficos
Autores principales:	Lee, Jean K., Stewart-Jones, Guillaume, Dong, Tao, Harlos, Karl, Di Gleria, Kati, Dorrell, Lucy, Douek, Daniel C., van der Merwe, P. Anton, Jones, E. Yvonne, McMichael, Andrew J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211951/ https://www.ncbi.nlm.nih.gov/pubmed/15583017 http://dx.doi.org/10.1084/jem.20041251

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