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Loss of HIV-1–specific CD8(+) T Cell Proliferation after Acute HIV-1 Infection and Restoration by Vaccine-induced HIV-1–specific CD4(+) T Cells

Virus-specific CD8(+) T cells are associated with declining viremia in acute human immunodeficiency virus (HIV)1 infection, but do not correlate with control of viremia in chronic infection, suggesting a progressive functional defect not measured by interferon γ assays presently used. Here, we demon...

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Detalles Bibliográficos
Autores principales: Lichterfeld, Mathias, Kaufmann, Daniel E., Yu, Xu G., Mui, Stanley K., Addo, Marylyn M., Johnston, Mary N., Cohen, Daniel, Robbins, Gregory K., Pae, Eunice, Alter, Galit, Wurcel, Alysse, Stone, David, Rosenberg, Eric S., Walker, Bruce D., Altfeld, Marcus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211961/
https://www.ncbi.nlm.nih.gov/pubmed/15381726
http://dx.doi.org/10.1084/jem.20041270