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Loss of HIV-1–specific CD8(+) T Cell Proliferation after Acute HIV-1 Infection and Restoration by Vaccine-induced HIV-1–specific CD4(+) T Cells
Virus-specific CD8(+) T cells are associated with declining viremia in acute human immunodeficiency virus (HIV)1 infection, but do not correlate with control of viremia in chronic infection, suggesting a progressive functional defect not measured by interferon γ assays presently used. Here, we demon...
Autores principales: | Lichterfeld, Mathias, Kaufmann, Daniel E., Yu, Xu G., Mui, Stanley K., Addo, Marylyn M., Johnston, Mary N., Cohen, Daniel, Robbins, Gregory K., Pae, Eunice, Alter, Galit, Wurcel, Alysse, Stone, David, Rosenberg, Eric S., Walker, Bruce D., Altfeld, Marcus |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211961/ https://www.ncbi.nlm.nih.gov/pubmed/15381726 http://dx.doi.org/10.1084/jem.20041270 |
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