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Differential Requirements for Vav Proteins in DAP10- and ITAM-mediated NK Cell Cytotoxicity
Natural killer (NK) cells express multiple activating receptors that initiate signaling cascades through DAP10- or immunoreceptor tyrosine-based activation motif–containing adapters, including DAP12 and FcRγ. Among downstream signaling mediators, the guanine nucleotide exchange factor Vav1 carries o...
Autores principales: | Cella, Marina, Fujikawa, Keiko, Tassi, Ilaria, Kim, Sunjin, Latinis, Kevin, Nishi, Shinzo, Yokoyama, Wayne, Colonna, Marco, Swat, Wojciech |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211968/ https://www.ncbi.nlm.nih.gov/pubmed/15365099 http://dx.doi.org/10.1084/jem.20031847 |
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