Suppressor T Cells in Human Diseases

Although central and peripheral tolerance are important for the regulation of human immune responses to self- and microbial antigens, an important role of suppressor CD4(+) CD25(+) T cells is suggested from the recent investigations of human autoimmune diseases and HIV. These new data provide increa...

Descripción completa

Detalles Bibliográficos
Autores principales: Baecher-Allan, Clare, Hafler, David A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211973/
https://www.ncbi.nlm.nih.gov/pubmed/15280423
http://dx.doi.org/10.1084/jem.20040812
_version_ 1782148594981142528
author Baecher-Allan, Clare
Hafler, David A.
author_facet Baecher-Allan, Clare
Hafler, David A.
author_sort Baecher-Allan, Clare
collection PubMed
description Although central and peripheral tolerance are important for the regulation of human immune responses to self- and microbial antigens, an important role of suppressor CD4(+) CD25(+) T cells is suggested from the recent investigations of human autoimmune diseases and HIV. These new data provide increasing evidence that altered function of CD4(+) CD25(+) T cells may be an important factor in a wide range of human inflammatory and infectious diseases.
format Text
id pubmed-2211973
institution National Center for Biotechnology Information
language English
publishDate 2004
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-22119732008-03-11 Suppressor T Cells in Human Diseases Baecher-Allan, Clare Hafler, David A. J Exp Med Commentary Although central and peripheral tolerance are important for the regulation of human immune responses to self- and microbial antigens, an important role of suppressor CD4(+) CD25(+) T cells is suggested from the recent investigations of human autoimmune diseases and HIV. These new data provide increasing evidence that altered function of CD4(+) CD25(+) T cells may be an important factor in a wide range of human inflammatory and infectious diseases. The Rockefeller University Press 2004-08-02 /pmc/articles/PMC2211973/ /pubmed/15280423 http://dx.doi.org/10.1084/jem.20040812 Text en Copyright © 2004, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Baecher-Allan, Clare
Hafler, David A.
Suppressor T Cells in Human Diseases
title Suppressor T Cells in Human Diseases
title_full Suppressor T Cells in Human Diseases
title_fullStr Suppressor T Cells in Human Diseases
title_full_unstemmed Suppressor T Cells in Human Diseases
title_short Suppressor T Cells in Human Diseases
title_sort suppressor t cells in human diseases
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211973/
https://www.ncbi.nlm.nih.gov/pubmed/15280423
http://dx.doi.org/10.1084/jem.20040812
work_keys_str_mv AT baecherallanclare suppressortcellsinhumandiseases
AT haflerdavida suppressortcellsinhumandiseases

Ejemplares similares