Mesothelin-specific CD8(+) T Cell Responses Provide Evidence of In Vivo Cross-Priming by Antigen-Presenting Cells in Vaccinated Pancreatic Cancer Patients

Tumor-specific CD8(+) T cells can potentially be activated by two distinct mechanisms of major histocompatibility complex class I–restricted antigen presentation as follows: direct presentation by tumor cells themselves or indirect presentation by professional antigen-presenting cells (APCs). Howeve...

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Detalles Bibliográficos
Autores principales: Thomas, Amy Morck, Santarsiero, Lynn M., Lutz, Eric R., Armstrong, Todd D., Chen, Yi-Cheng, Huang, Lan-Qing, Laheru, Daniel A., Goggins, Michael, Hruban, Ralph H., Jaffee, Elizabeth M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211979/
https://www.ncbi.nlm.nih.gov/pubmed/15289501
http://dx.doi.org/10.1084/jem.20031435

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