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Limited T Cell Receptor Diversity of HCV-specific T Cell Responses Is Associated with CTL Escape

Escape mutations are believed to be important contributors to immune evasion by rapidly evolving viruses such as hepatitis C virus (HCV). We show that the majority of HCV-specific cytotoxic T lymphocyte (CTL) responses directed against viral epitopes that escaped immune recognition in HCV-infected c...

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Detalles Bibliográficos
Autores principales:	Meyer-Olson, Dirk, Shoukry, Naglaa H., Brady, Kristen W., Kim, Helen, Olson, Douglas P., Hartman, Kelly, Shintani, Ayumi K., Walker, Christopher M., Kalams, Spyros A.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211982/ https://www.ncbi.nlm.nih.gov/pubmed/15289502 http://dx.doi.org/10.1084/jem.20040638

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