Cargando…

Limited T Cell Receptor Diversity of HCV-specific T Cell Responses Is Associated with CTL Escape

Escape mutations are believed to be important contributors to immune evasion by rapidly evolving viruses such as hepatitis C virus (HCV). We show that the majority of HCV-specific cytotoxic T lymphocyte (CTL) responses directed against viral epitopes that escaped immune recognition in HCV-infected c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meyer-Olson, Dirk, Shoukry, Naglaa H., Brady, Kristen W., Kim, Helen, Olson, Douglas P., Hartman, Kelly, Shintani, Ayumi K., Walker, Christopher M., Kalams, Spyros A.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211982/ https://www.ncbi.nlm.nih.gov/pubmed/15289502 http://dx.doi.org/10.1084/jem.20040638

Ejemplares similares

Virus escape from CTL recognition
Publicado: (1994)

HIV CTL escape: at what cost?
por: Smith, Stephen M
Publicado: (2004)

Broad CTL Response in Early HIV Infection Drives Multiple Concurrent CTL Escapes
por: Leviyang, Sivan, et al.
Publicado: (2015)

Towards a Systems Immunology Approach to Understanding Correlates of Protective Immunity against HCV
por: Shoukry, Naglaa H.
Publicado: (2021)

Structured Observations Reveal Slow HIV-1 CTL Escape
por: Roberts, Hannah E., et al.
Publicado: (2015)

CTL Escape and Viral Fitness in HIV/SIV Infection
por: Seki, Sayuri, et al.
Publicado: (2012)

A Tale of Two Viruses: Immunological Insights Into HCV/HIV Coinfection
por: Gobran, Samaa T., et al.
Publicado: (2021)

Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection
por: Ganusov, Vitaly V, et al.
Publicado: (2006)

CTL Escape Mediated by Proteasomal Destruction of an HIV-1 Cryptic Epitope
por: Cardinaud, Sylvain, et al.
Publicado: (2011)

Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape
por: Karlsson, Annika C., et al.
Publicado: (2007)

Stable Cytotoxic T Cell Escape Mutation in Hepatitis C Virus Is Linked to Maintenance of Viral Fitness
por: Uebelhoer, Luke, et al.
Publicado: (2008)

IFN‐λ3 polymorphism indirectly influences NK cell phenotype and function during acute HCV infection
por: Depla, Marion, et al.
Publicado: (2016)

Determinants of HIV-1 Mutational Escape From Cytotoxic T Lymphocytes
por: Yang, Otto O., et al.
Publicado: (2003)

Phylogenetic Dependency Networks: Inferring Patterns of CTL Escape and Codon Covariation in HIV-1 Gag
por: Carlson, Jonathan M., et al.
Publicado: (2008)

Variable Processing and Cross-presentation of HIV by Dendritic Cells and Macrophages Shapes CTL Immunodominance and Immune Escape
por: Dinter, Jens, et al.
Publicado: (2015)

P09-10. Impact of CTL escape mutations in HIV-1 Nef on viral replication
por: Oniangue-Ndza, C, et al.
Publicado: (2009)

A viral CTL escape mutation leading to immunoglobulin-like transcript 4–mediated functional inhibition of myelomonocytic cells
por: Lichterfeld, Mathias, et al.
Publicado: (2007)

Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA
por: Leslie, Alasdair, et al.
Publicado: (2005)

Variable Fitness Impact of HIV-1 Escape Mutations to Cytotoxic T Lymphocyte (CTL) Response
por: Troyer, Ryan M., et al.
Publicado: (2009)

Impact of transmitted CTL escape mutations on replicative capacity and HIV pathogenesis in early infection
por: Prince, J, et al.
Publicado: (2012)

Within-Epitope Interactions Can Bias CTL Escape Estimation in Early HIV Infection
por: Garcia, Victor, et al.
Publicado: (2017)

Mutational escape from CD8(+) T cell immunity: HCV evolution, from chimpanzees to man
por: Bowen, David G., et al.
Publicado: (2005)

Hepatitis C Vaccines, Antibodies, and T Cells
por: Shoukry, Naglaa H.
Publicado: (2018)

Increased CD56(bright) NK cells in HIV-HCV co-infection and HCV mono-infection are associated with distinctive alterations of their phenotype
por: Bhardwaj, Suvercha, et al.
Publicado: (2016)

CD127 Expression, Exhaustion Status and Antigen Specific Proliferation Predict Sustained Virologic Response to IFN in HCV/HIV Co-Infected Individuals
por: Kared, Hassen, et al.
Publicado: (2014)

A novel category of antigens enabling CTL immunity to tumor escape variants: Cinderella antigens
por: Seidel, Ursula J. E., et al.
Publicado: (2011)

OA06-03. Dynamics of CTL epitope escape and reversion in an African subtype C cohort
por: Schaefer, M, et al.
Publicado: (2009)

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations
por: Deng, Kai, et al.
Publicado: (2015)

Transmission of HIV-1 CTL Escape Variants Provides HLA-Mismatched Recipients with a Survival Advantage
por: Chopera, Denis R., et al.
Publicado: (2008)

Kinetics of HIV-Specific CTL Responses Plays a Minimal Role in Determining HIV Escape Dynamics
por: Yang, Yiding, et al.
Publicado: (2018)

CD8 Epitope Escape and Reversion in Acute HCV Infection
por: Timm, Joerg, et al.
Publicado: (2004)

Altered Thymic Function during Interferon Therapy in HCV-Infected Patients
por: Beq, Stephanie, et al.
Publicado: (2012)

Quantification of the Relative Importance of CTL, B Cell, NK Cell, and Target Cell Limitation in the Control of Primary SIV-Infection
por: Elemans, Marjet, et al.
Publicado: (2011)

The Critical Need for CD4 Help in Maintaining Effective Cytotoxic T Lymphocyte Responses
por: Kalams, Spyros A., et al.
Publicado: (1998)

Maintenance of viral suppression in HIV-1–infected HLA-B*57(+) elite suppressors despite CTL escape mutations
por: Bailey, Justin R., et al.
Publicado: (2006)

Mutational Escape in HIV-1 CTL Epitopes Leads to Increased Binding to Inhibitory Myelomonocytic MHC Class I Receptors
por: Yang, Yue, et al.
Publicado: (2010)

Genetic divergence of HIV-1 B subtype in Italy over the years 2003–2016 and impact on CTL escape prevalence
por: Alteri, Claudia, et al.
Publicado: (2018)

Differential immune transcriptomic profiles between vaccinated and resolved HCV reinfected subjects
por: Mazouz, Sabrina, et al.
Publicado: (2022)

P09-07. Balancing reversion of CTL and neutralizing antibody escape mutations within HIV-1 Env upon transmission
por: Peut, V, et al.
Publicado: (2009)

Suppression of HIV-Specific and Allogeneic T Cell Activation by Human Regulatory T Cells Is Dependent on the Strength of Signals
por: Antons, Amanda K., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_uhmlmvicp1csk3oifcvkj2bkf5