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Loss of Synchronized Retinal Phagocytosis and Age-related Blindness in Mice Lacking αvβ5 Integrin

Daily phagocytosis by the retinal pigment epithelium (RPE) of spent photoreceptor outer segment fragments is critical for vision. In the retina, early morning circadian photoreceptor rod shedding precedes synchronized uptake of shed photoreceptor particles by RPE cells. In vitro, RPE cells use the i...

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Detalles Bibliográficos
Autores principales: Nandrot, Emeline F., Kim, Yoonhee, Brodie, Scott E., Huang, Xiaozhu, Sheppard, Dean, Finnemann, Silvia C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211990/
https://www.ncbi.nlm.nih.gov/pubmed/15596525
http://dx.doi.org/10.1084/jem.20041447