Cargando…

HIV-specific Cytotoxic T Cells from Long-Term Survivors Select a Unique T Cell Receptor

HIV-specific cytotoxic T lymphocytes (CTL) are important in controlling HIV replication, but the magnitude of the CTL response does not predict clinical outcome. In four donors with delayed disease progression we identified Vβ13.2 T cell receptors (TCRs) with very similar and unusually long β-chain...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Tao, Stewart-Jones, Guillaume, Chen, Nan, Easterbrook, Philippa, Xu, Xiaoning, Papagno, Laura, Appay, Victor, Weekes, Michael, Conlon, Chris, Spina, Celsa, Little, Susan, Screaton, Gavin, van der Merwe, Anton, Richman, Douglas D., McMichael, Andrew J., Jones, E. Yvonne, Rowland-Jones, Sarah L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212004/
https://www.ncbi.nlm.nih.gov/pubmed/15596521
http://dx.doi.org/10.1084/jem.20032044