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GITR Activation Induces an Opposite Effect on Alloreactive CD4(+) and CD8(+) T Cells in Graft-Versus-Host Disease

Glucocorticoid-induced tumor necrosis factor receptor family-related gene (GITR) is a member of the tumor necrosis factor receptor (TNFR) family that is expressed at low levels on unstimulated T cells, B cells, and macrophages. Upon activation, CD4(+) and CD8(+) T cells up-regulate GITR expression,...

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Detalles Bibliográficos
Autores principales:	Muriglan, Stephanie J., Ramirez-Montagut, Teresa, Alpdogan, Onder, van Huystee, Thomas W., Eng, Jeffrey M., Hubbard, Vanessa M., Kochman, Adam A., Tjoe, Kartono H., Riccardi, Carlo, Pandolfi, Pier Paolo, Sakaguchi, Shimon, Houghton, Alan N., van den Brink, Marcel R.M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212013/ https://www.ncbi.nlm.nih.gov/pubmed/15249593 http://dx.doi.org/10.1084/jem.20040116

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