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Unique Clinical and Pathological Features in HLA-DRB1*0401–restricted MBP 111–129–specific Humanized TCR Transgenic Mice

Amino acid residues 111–129 represent an immunodominant epitope of myelin basic protein (MBP) in humans with human leukocyte antigen (HLA)-DRB1*0401 allele(s). The MBP 111–129–specific T cell clone MS2-3C8 was repeatedly isolated from a patient with multiple sclerosis (MS), suggesting an involvement...

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Detalles Bibliográficos
Autores principales:	Quandt, Jacqueline A., Baig, Mirza, Yao, Karen, Kawamura, Kazuyuki, Huh, Jaebong, Ludwin, Samuel K., Bian, Hong-Jin, Bryant, Mark, Quigley, Laura, Nagy, Zoltan A., McFarland, Henry F., Muraro, Paolo A., Martin, Roland, Ito, Kouichi
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212014/ https://www.ncbi.nlm.nih.gov/pubmed/15263029 http://dx.doi.org/10.1084/jem.20030994

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