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IFN-γ production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo

The significance of cytokine production by CD4(+) regulatory T (T reg) cells after antigen exposure in vivo and its impact on their regulatory activity remains unclear. Pretreatment with donor alloantigen under the cover of anti-CD4 therapy generates alloantigen reactive T reg cells that can prevent...

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Detalles Bibliográficos
Autores principales: Sawitzki, Birgit, Kingsley, Cherry I., Oliveira, Vanessa, Karim, Mahzuz, Herber, Manuela, Wood, Kathryn J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212028/
https://www.ncbi.nlm.nih.gov/pubmed/15967822
http://dx.doi.org/10.1084/jem.20050419