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IFN-γ production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo
The significance of cytokine production by CD4(+) regulatory T (T reg) cells after antigen exposure in vivo and its impact on their regulatory activity remains unclear. Pretreatment with donor alloantigen under the cover of anti-CD4 therapy generates alloantigen reactive T reg cells that can prevent...
Autores principales: | Sawitzki, Birgit, Kingsley, Cherry I., Oliveira, Vanessa, Karim, Mahzuz, Herber, Manuela, Wood, Kathryn J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212028/ https://www.ncbi.nlm.nih.gov/pubmed/15967822 http://dx.doi.org/10.1084/jem.20050419 |
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