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Importance of integrin LFA-1 deactivation for the generation of immune responses

The dynamic regulation of ligand binding is considered crucial for integrin function. However, the importance of activity regulation for integrin function in vivo is largely unknown. Here, we have applied gene targeting to delete the GFFKR sequence of the lymphocyte function-associated antigen–1 (LF...

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Detalles Bibliográficos
Autores principales:	Semmrich, Monika, Smith, Andrew, Feterowski, Carolin, Beer, Sandra, Engelhardt, Britta, Busch, Dirk H., Bartsch, Bernadett, Laschinger, Melanie, Hogg, Nancy, Pfeffer, Klaus, Holzmann, Bernhard
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212031/ https://www.ncbi.nlm.nih.gov/pubmed/15955836 http://dx.doi.org/10.1084/jem.20041850

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