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Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4(+) T cells
Dendritic cells (DCs) are essential antigen-presenting cells for the induction of T cell immunity against pathogens such as human immunodeficiency virus (HIV)-1. At the same time, HIV-1 replication is strongly enhanced in DC–T cell clusters, potentially undermining this process. We found that immatu...
Autores principales: | Loré, Karin, Smed-Sörensen, Anna, Vasudevan, Jayanand, Mascola, John R., Koup, Richard A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212038/ https://www.ncbi.nlm.nih.gov/pubmed/15967828 http://dx.doi.org/10.1084/jem.20042413 |
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