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Shifts in targeting of class switch recombination sites in mice that lack μ switch region tandem repeats or Msh2
The mechanisms that target class switch recombination (CSR) to antibody gene switch (S) regions are unknown. Analyses of switch site locations in wild-type mice and in mice that lack the Sμ tandem repeats show shifts indicating that a 4–5-kb DNA domain (bounded upstream by the Iμ promoter) is access...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212040/ https://www.ncbi.nlm.nih.gov/pubmed/15955838 http://dx.doi.org/10.1084/jem.20042491 |