Invariant Chain–independent Function of H-2M in the Formation of Endogenous Peptide–Major Histocompatibility Complex Class II Complexes In Vivo

Efficient loading of major histocompatibility complex class II molecules with peptides requires the invariant chain (Ii) and the class II–like molecule H-2M. Recent in vitro biochemical studies suggest that H2-M may function as a chaperone to rescue empty class II dimers. To test this hypothesis in...

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Detalles Bibliográficos
Autores principales: Kovats, Susan, Grubin, Catherine E., Eastman, Susan, deRoos, Paul, Dongre, Ashok, Kaer, Luc Van, Rudensky, Alexander Y.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212101/
https://www.ncbi.nlm.nih.gov/pubmed/9432982

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