Cargando…
Nuclear Factor (NF)-κB2 (p100/p52) Is Required for Normal Splenic Microarchitecture and B Cell–mediated Immune Responses
The nfkb2 gene is a member of the Rel/NF-κB family of transcription factors. COOH-terminal deletions and rearrangements of this gene have been associated with the development of human cutaneous T cell lymphomas, chronic lymphocytic leukemias, and multiple myelomas. To further investigate the functio...
Autores principales: | Caamaño, Jorge H., Rizzo, Cheryl A., Durham, Stephen K., Barton, Debra S., Raventós-Suárez, Carmen, Snapper, Clifford M., Bravo, Rodrigo |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212102/ https://www.ncbi.nlm.nih.gov/pubmed/9432976 |
Ejemplares similares
-
Mice Deficient in Nuclear Factor (NF)-κB/p52 Present with Defects in Humoral Responses, Germinal Center Reactions, and Splenic Microarchitecture
por: Franzoso, Guido, et al.
Publicado: (1998) -
p50–NF-κB Complexes Partially Compensate for the Absence of RelB: Severely Increased Pathology in p50(−)
(/−)
relB(−)
(/−)Double-knockout Mice
por: Weih, Falk, et al.
Publicado: (1997) -
p100 Deficiency Is Insufficient for Full Activation of the Alternative NF-κB Pathway: TNF Cooperates with p52-RelB in Target Gene Transcription
por: Lovas, Agnes, et al.
Publicado: (2012) -
Origin of the Functional Distinctiveness of NF-κB/p52
por: Ghosh, Gourisankar, et al.
Publicado: (2021) -
TRIM14 Promotes Noncanonical NF‐κB Activation by Modulating p100/p52 Stability via Selective Autophagy
por: Chen, Meixin, et al.
Publicado: (2019)